Radiesse+ Treatment and Its Alternatives

Radiesse+ and its collagen-boosting magic are a favourite in aesthetic medicine circles. But is it the right fit for your client’s goals, and which alternatives can replace it if not? Radiesse’s both immediate and long-lasting effects certainly make it tempting, but the situation may easily call for something different. 

What Is Radiesse+?

Radiesse+ is an FDA-approved dermal filler that consists of calcium-based microspheres in a water-based gel carrier. Its primary use is to reduce wrinkles, lift and contour the face, and improve skin texture.

In 2025, Radiesse is among the top cosmetic products in the Canadian and US markets. While it has numerous advantages, like any medical treatment, it also comes with its own set of aspects to consider.

Understanding all the Radiesse effects and exploring alternative treatments can help you make informed decisions for your practice and patients.

Radiesse+ Treatment Areas

First of all — the basics. These are the primary target areas for Radiesse treatment: 

• Midface for restoring volume to the cheeks, creating a more youthful and defined appearance;
• Nasolabial folds, addressing the lines extending from the nose to the corners of the mouth;
• Marionette lines, improving the appearance of downward-turned mouth corners;
• Chin, creating a more balanced facial profile;
• Jawline, defining and lifting the jawline, reducing the appearance of jowls. 

Radiesse+ treatment is a flexible beauty tool that works well with many facial areas. It is also one of the reasons why many choose it for their practice.

Radiesse+ Properties 

These days, Radiesse is one of the most popular facial fillers because of its unique features and qualities:

1. Immediate improvement is achieved because Radiesse contains a gel that instantly fills wrinkles, providing a smoother and more youthful appearance right after application;
2. Long-lasting effects with results that are even more noticeable after one week and lasting for more than a year. These miracles are supported by calcium hydroxylapatite (CaHA) stimulating the body’s own natural collagen and elastin production;
3. Non-allergenic, so there is less chance of your patients experiencing adverse effects. However, we still recommend conducting an allergy test before the procedure. Radiesse is fully compatible with the body’s tissue, as the synthetic calcium hydroxylapatite is a naturally occurring substance which is actually the same material found in our bones and teeth. That also means that the body won’t reject it.

The combination of these effects appeals to many patients. They often prefer this mix of gradual enhancement and some instant results.

Recommendations for Faster Recovery

One drawback of Radiesse’s long-lasting effects is that if a patient doesn’t like the results, they may have to wait 12 to 18 months for the filler to dissolve naturally. It puts extra importance on the quality of your procedure.

When informing clients about the procedure, share these tips to help minimize side effects, reduce the risk of complications, and speed up recovery after Radiesse injections.

• To minimize bruising, it is necessary to avoid medications that thin the blood, such as Aspirin, Ibuprofen (Advil, Motrin), and vitamin E, for several days before and after the treatment;
• Alcohol and caffeine also increase bruising, so it’s best to avoid or limit their consumption during this period;
• Avoid using Glycolic Acid, Alpha Hydroxy Acids higher than 10%, Retinoids, creams and other cosmetic or pharmaceutical products with Vitamin C;
• Do not subject the treatment area to waxing, bleaching, tweezing, or hair removal creams;
• Avoid or minimize unprotected sun exposure;
• Refrain from sports and intense physical activity.

When Radiesse is injected correctly, the potential for side effects is significantly reduced. Injections should be performed by a trained, experienced, certified professional.

Alternatives to Radiesse+

The best filler for a patient depends on their individual needs, desired outcomes, and medical history. If Radiesse isn’t suitable, several other dermal fillers offer similar benefits, each with its unique properties and side effect profiles.

Here’s a brief overview of some alternatives:

Hyaluronic Acid (HA) Fillers

These are the most common types of dermal filler. HA fillers come in various formulations that work best on different facial areas for desired outcomes. 

• Examples: Juvederm, Restylane;
• Benefits: Hyaluronic acid fillers have a lower risk of complications;
• Duration: Results last 6-12 months, depending on the product.

These fillers are typically reversible with hyaluronidase, an enzyme that breaks down hyaluronic acid.

Poly-L-Lactic Acid (PLLA) Fillers

These fillers stimulate collagen production for long-lasting results. They are your top choice for clients who want volumizing and structural support. 

• Example: Sculptra;
• Benefits: Stimulates collagen production, thus requiring fewer procedures for lasting results;
• Duration: Effects can last up to two years.

PLLA fillers take longer to show results than other fillers and may cause temporary swelling.

Fat Dissolvers 

Fat dissolvers are a non-surgical solution for patients in need of targeted fat reduction. A mix of natural active ingredients interacts with the fat tissue directly for maximum effects.

• Example: Lemon Bottle;
• Benefits: Non-invasive targeted fat reduction and minimal downtime;
• Duration: Permanent with long-term effects depending on the patient’s lifestyle.

It’s a highly effective treatment, but the client will need to maintain the results with diet and regular exercise.

Mesotherapy

Mesotherapy injectables deliver a blend of nutrients directly into the skin with a focus on hydration, firmness, and overall skin health. 

• Example: Jalupro;
• Benefits: Offers better moisture retention and helps with fine lines for those in need of subtle results
• Duration: Between 12 to 18 months

Mesotherapy bridges the gap between skincare and injectable treatments, offering a natural glow and revitalized skin.

Conclusion

Dermal fillers give your patients a fantastic opportunity to get the look they want without surgical intervention. What’s more, some of the effects can even be reversible if needed. Radiesse+ treatment is one of the best options for injections since it is non-allergic and suitable for various skin types and areas.